When picking or editing a gaming or anime PFP, focus on a strong silhouette and...

https://griffinphut760.theglensecret.com/how-do-i-keep-the-eyes-readable-in-a-tiny-profile-picture

When picking or editing a gaming or anime PFP, focus on a strong silhouette and high contrast to keep it clear at small sizes. Crop the face close for better recognition, and use a simple background to avoid distractions